The Cryogenic Chambers are Antigen's devices seen in Underworld: Awakening. They are located within Antigen's headquarters. It is a device designed to hold living specimens in a coma, via a combination of cold and pressure with the intent to preserve the subjects for long periods of time for further study and experimentation. The Vampire Death Dealer Selene and the Hybrid Michael Corvin were both held prisoners in cryogenic stasis for twelve years before their respective escapes. The chambers could be also used to hold humans and Lycans.
Two cryogenic chambers are shown during the course of Underworld: Awakening, one holding Selene and the other holding Michael. Selene is locked in her chamber for twelve years, until her daughter Eve rescues her by triggering the chamber's Defrost sequence. Selene is then able to awaken and break out of the chamber. For reasons unknown, all of her Death Dealer clothes have been stored in the same room during the entirety of her induced coma.
Selene accidentally finds Michael's cryogenic chamber when she returns to Antigen to rescue her daughter, and shoots it to disable the system enough for Michael to wake up and escape. She later returns for him with Eve, but Michael has already fled the building.
- The cryogenic chambers in Awakening and the fact that Selene & Michael's characters in the franchise essentially skipped over a period of time while the world around them changed, is not unlike when the Vampire Elders would go into hibernation during their turns in The Chain. The cryogenic chambers are like the Elders' sarcophagi. Selene and Michael were even placed in them upside-down like the Elders were during their long sleep.
- ANTIGEN computer voice: "Defrost sequence initiated."
- ANTIGEN computer voice: "Lowering compression in Subject 1 cryo-chamber."
- ANTIGEN computer voice: "Defrost sequence complete."
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