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Selene, David, Semira, (Possibly Lena) Jacob Lane, Quint Lane, and Marius are all Evolved and Enhanced by Corvinus Strain. Selene was turned into a Evolved Vampire directly by drinking Alexander Corvinus's blood, then she sired David, possibly Lena, and, unwillingly, Semira. Jacob and Quint Lane, and later Marius were made into Evolved Lycan by Corvinus Strain by drinking and/or injecting themselves with the hybrid blood of Michael and Eve.

Jacob and Quint could genetically extract the pure Corvinus Strain from Eve, making them more enhanced as they kept inoculating themselves with the serum made from her blood. Marius, however, had to inject himself and drink directly from Michael's hybrid blood, resulting in a transformation even more unstable and temporary than the former Evolved Lycan, probably caused by the high concentration of the incompatible Vampire Strain present in Michael's blood.

It should be noted that the Corvinus-Strain Hybrid are not "true" Hybrids, as they are more of an Evolved form/new breed of Vampires and Lycans since their DNA is mostly the same and not a mixture like the Lycan/Vampire Hybrids.

Also, technically, all Vampires and Lycans already carry the Corvinus Strain, mutated with the animals DNA, and the assimilation of the "pure" Corvinus Strain simply strengthens/evolves their own existing Strain (their physical abilities are amplified and their weakness eliminated).

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